Reversed-phase high-performance liquid chromatography on porous copolymers of different chemical structure

The influence of chemical structure of porous polymers on the chromatographic properties of high-performance liquid chromatography columns was studied. Columns were packed with four different porous copolymers: di(methacryloyloxymethyl)naphthalene–divinylbenzene containing ester functional groups, 4,4′-bis(maleimido)diphenylmethane–divinylbenzene with imide groups, di(4,4′-dimethacrylphenyl)sulfone–divinylbenzene which contains sulphonyl groups, and styrene–divinylbenzene with any functional groups. Using the alkyl aryl ketone scale, the retention indices of five homologous series (alkylbenzenes, alkyl aryl ketones, N-alkylanilines, alkyl aryl ethers, alkylbenzoates) and column test compounds (toluene, nitrobenzene, p-cresol, 2-phenylethanol, N-methylaniline) were calculated. Their values were used for comparison of the selectivities of the studied polymeric packings.