Title of article
Investigation of pharmaceutical high-performance liquid chromatography assay bias using experimental design
Author/Authors
Chen، نويسنده , , Jian-Ge and Glancy، نويسنده , , Kelly and Chen، نويسنده , , Xiaohong and Alasandro، نويسنده , , Mark، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
11
From page
63
To page
73
Abstract
This article presents a systematic approach to investigate, document, and eliminate pharmaceutical HPLC assay bias using experimental design. This is the first article to describe the application of experimental design in the area of assay bias. It is found that both formulation and analytical variables can contribute to pharmaceutical HPLC assay bias using model compounds and formulations.
Keywords
XP 280 , DMP 543
Journal title
Journal of Chromatography A
Serial Year
2001
Journal title
Journal of Chromatography A
Record number
1507881
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