High-performance liquid chromatography analysis of ten dyes for control of safety of commercial articles

Two high-performance liquid chromatographic methods, with ultraviolet–visible spectrophotometry detection (HPLC-UV/Vis) and with tandem mass spectrometry triple quadrupole interfaced with positive ion mode electrospray ionization detection (HPLC–ESI(+)-QqQ-MS/MS), for determination and quantification of ten commercial dyes are proposed for control in commercial products. Multiple peaks observed for some of the studied dyes in HPLC-UV/Vis chromatograms forced to obtain structural information by HPLC–ESI-MS/MS method with scan mode. The quality parameters of the two proposed chromatographic methods were evaluated for different requirements of normative, showing detection (LODs) and quantification (LOQs) limits around 60–890 and 200–2990 μg L−1 for HPLC-UV/Vis, and 4.54–14.3 and 15.0–47.6 μg L−1 for HPLC–ESI(+)-QqQ-MS/MS.