Title of article :
Quantification of amino acid ionic liquids using liquid chromatography–mass spectrometry
Author/Authors :
Tang، نويسنده , , Fei and Wu، نويسنده , , Kangkang and Nie، نويسنده , , Zhou and Ding، نويسنده , , Li and Liu، نويسنده , , Qian and Yuan، نويسنده , , Jinbin and Guo، نويسنده , , Manli and Yao، نويسنده , , Shouzhuo، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Pages :
7
From page :
175
To page :
181
Abstract :
Amino acid ionic liquids (AAILs) containing imidazolium cations and amino acid (AA) anions, were synthesized and applied as task-specific ionic liquids. A sensitive and fast liquid chromatography–mass spectrometry (LC–MS) method was established for the quantitative analysis of 20 AAILs. Using ion pairing-reversed phase liquid chromatography technique, heptafluorobutyric acid was used as ion-pairing reagent to increase the retention of AAILs. Based on the zwitterionity of amino acid, this method was proposed to determine both the cation and the anion of AAILs simultaneously. The limit of detection of this method is down to 1–15 ng/mL and the analysis time is less than 15 min. According to the analytical data of seven selected AAILs, we found that the content of amino acid anion is always lower than that of butyl methyl imidazolium cation in AAILs. Moreover, the molar ratio of imidazolium cation to amino acid anion is dependent on the chemical property of the amino acid. These results supplied useful information on the interaction of imidazolium cation with acidic, basic, neutral and non-polar amino acids in AAILs.
Keywords :
Amino acid ionic liquid , task-specific ionic liquid , Quantification , Ion pair-reversed phase chromatography , LC–MS , Molar ratio , PI , Polarity
Journal title :
Journal of Chromatography A
Serial Year :
2008
Journal title :
Journal of Chromatography A
Record number :
1511290
Link To Document :
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