Title of article :
Determination of organophosphorus pesticides and metabolites in cereal-based baby foods and wheat flour by means of ultrasound-assisted extraction and hollow-fiber liquid-phase microextraction prior to gas chromatography with nitrogen phosphorus detection
Author/Authors :
Lidia M. and Gonzلlez-Curbelo، نويسنده , , Miguel ءngel and Hernلndez-Borges، نويسنده , , Javier and Borges-Miquel، نويسنده , , Teresa Marيa and Rodrيguez-Delgado، نويسنده , , Miguel ءngel، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Pages :
9
From page :
166
To page :
174
Abstract :
A new method based on hollow-fiber liquid-phase microextraction (HF-LPME) has been developed for the determination of a group of organophosphorus pesticides, including some of their metabolites, in two commercial cereal-based baby foods and one wheat flour prior to gas chromatography-nitrogen phosphorus detection. Samples were first extracted by ultrasound-assisted extraction with acetonitrile (ACN) containing 1.25% (v/v) of formic acid. After evaporation and reconstitution in Milli-Q water, the HF-LPME procedure, using 1-octanol as extraction solvent, was applied followed by a desorption step in ACN, which clearly improved the performance of the technique. The effects of sample pH, ionic strength, stirring rate, extraction temperature and time as well as the desorption procedure were investigated. Under the optimum conditions that involved the extraction of the analytes from 10 mL of the water reconstituted extract at pH 7.0 containing 5% (w/v) of NaCl for 45 min at 960 rpm, the method was validated in terms of linearity, precision and accuracy. The limits of detection (LODs) were between 0.29 and 3.20 μg/kg. The extraction of Milli-Q water, as an example of the applicability of the procedure to aqueous samples, allowed achieving LODs in the range 0.01–0.04 μg/L. Such values, together with the ones achieved for the rest of the samples, are below or equal to the maximum residue limits specified by the European Union.
Keywords :
Organophosphorus pesticides , Hollow-fiber liquid-phase microextraction , Ultrasound-assisted extraction , Cereal-based baby foods , Gas chromatography-nitrogen phosphorus detection , wheat flour
Journal title :
Journal of Chromatography A
Serial Year :
2013
Journal title :
Journal of Chromatography A
Record number :
1518398
Link To Document :
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