Title of article
Size-exclusion chromatography based on silica-diol for the analysis of the proinsulin fusion protein
Author/Authors
Gusarova، نويسنده , , V. and Vorobjeva، نويسنده , , T. and Gusarov، نويسنده , , D. and Lasman، نويسنده , , V. and Bayramashvili، نويسنده , , D.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
157
To page
162
Abstract
Size-exclusion chromatography based on silica-diol sorbent was employed to analyze the recombinant proinsulin fusion protein obtained during the process of refolding and the following ion-exchange purification. The assay was qualified as a control method estimating its accuracy, precision, linearity, limit of detection, limits of quantitation, specificity, and robustness. The results show the reliability for the intended use.
Keywords
size-exclusion chromatography , Validation , QUALIFICATION , Proinsulin fusion protein
Journal title
Journal of Chromatography A
Serial Year
2007
Journal title
Journal of Chromatography A
Record number
1522741
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