Title of article
Chiral separation of anticholinergic drug enantiomers in nonaqueous capillary electrophoresis
Author/Authors
Du، نويسنده , , Guohua and Zhang، نويسنده , , Shuzhen and Xie، نويسنده , , Jianwei and Zhong، نويسنده , , Bohua and Liu، نويسنده , , Keliang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
6
From page
195
To page
200
Abstract
Nonaqueous capillary electrophoretic (NACE) method for the separation of nine structurally similar chiral anticholinergic drugs was developed. The eight drug enantiomers were separated on baseline within 18 min using 20 mM phosphoric acid and 10 mM NaOH, containing 10 mM heptakis(2,3-dimethyl-6-sulfato)-β-cyclodextrin (HDMS-β-CD) in methanol. The results were compared with those obtained in the high performance liquid chromatography system.
Keywords
Nonaqueous capillary electrophoresis , Methanol background electrolyte , Heptakis(2 , Enantiomer separation , 3-dimethyl-6-sulfato)-?-cyclodextrin , Anticholinergic drugs
Journal title
Journal of Chromatography A
Serial Year
2005
Journal title
Journal of Chromatography A
Record number
1524022
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