Title of article
Development of a headspace gas chromatography method to determine residual aliphatic amines in oligonucleotides
Author/Authors
Von Wald، نويسنده , , Grant and Albers، نويسنده , , Dave and Nicholson، نويسنده , , Larry and Langhorst، نويسنده , , Marsha and Bell، نويسنده , , Bruce، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
179
To page
182
Abstract
A headspace gas chromatographic method has been developed for analysis of aliphatic amines in oligonucleotides. The linearity was improved by including ammonia in the sample vials. Also, carryover of longer chain primary amines, hexylamine and octylamine, was substantially reduced by cleaning the injection syringe with ammonia and water vapor between sample injections.
Keywords
Aliphatic amines , Headspace gas chromatography
Journal title
Journal of Chromatography A
Serial Year
2005
Journal title
Journal of Chromatography A
Record number
1524079
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