New approach for evaluation of capillary column inverse gas chromatography

A mathematical model has been developed for the analysis of a capillary column IGC experiment. An important feature in the derivation of the model is the inclusion of Taylor dispersion effect. The model shows that Taylor dispersion effect has a very significant effect on elution profiles at low values of β and γ. Taylor dispersion effect causes more spread in the longitudinal direction and the peaks become broader. Taylor dispersion becomes more significant as β becomes smaller. The model presented in this paper is more general than the usual IGC models and sets criteria equations to determine under what conditions the Taylor dispersion effect can be made negligible. A comparison between the present and usual IGC models above and near the glass temperature of the polymer is conducted. The analysis also describes the effect of kurtosis on pulse dispersion at extremely low diffusivities.