Author/Authors :
Ru، نويسنده , , Qinhua Cindy and Katenhusen، نويسنده , , Richard A. and Zhu، نويسنده , , Luwang Andy and Silberman، نويسنده , , Jordan and Yang، نويسنده , , Song and Orchard، نويسنده , , Trevor J. and Brzeski، نويسنده , , Henry and Liebman، نويسنده , , Michael and Ellsworth، نويسنده , , Darrell L.، نويسنده ,
Abstract :
Human urine samples are ideal for proteomic profiling and have tremendous potential as sources of biomarkers. Multi-dimensional protein identification technology (MudPIT) is an effective approach to analyzing human urine or other fluids dominated by diverse metabolites. MudPIT analysis was used to identify 87 proteins in just 15 ml of human urine. A high throughput, reproducible, and sensitive technology, MudPIT may soon be used for more proteomic analyses of metabolites.
Keywords :
PROTEOMICS , Human urine , Metabolite analysis , Multi-dimensional protein identification technology
