Title of article :
Separation of cationic aracyl derivatives of betaines and related compounds
Author/Authors :
Storer، نويسنده , , Malina K. and McEntyre، نويسنده , , Christopher J. and Lever، نويسنده , , Michael، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Pages :
9
From page :
263
To page :
271
Abstract :
Cationic aracyl esters of betaines can be formed by alkylation with aracyl halides or trifluoromethanesulfonates. HPLC on a non-endcapped strong cation exchange (SCX) column gave high retention of these derivatives. Cation exchange HPLC may be carried out on a normal-phase (silica or alumina) column using a polar organic solvent (acetonitrile, propan-2-ol) containing an aqueous buffer with an organic cation and a hydrophilic anion. Selectivity is affected by the choice of organic solvent and buffer, e.g. alcohols decrease the retention times of hydroxybetaines such as carnitine. Retention is reduced by increasing the water content and the buffer concentration. Capillary electrophoresis migration times are affected by the choice of buffer anion, with low pH citrate buffers favoured.
Keywords :
HPLC , CE , mobile phase , Betaines , Separation , 2-Naphthacyl triflate
Journal title :
Journal of Chromatography A
Serial Year :
2006
Journal title :
Journal of Chromatography A
Record number :
1525073
Link To Document :
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