• Title of article

    Mitochondrial DNA damage and efficiency of ATP biosynthesis: mathematical model

  • Author/Authors

    Beregovskaya، نويسنده , , Neonila and Maiboroda، نويسنده , , Rostislav، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1995
  • Pages
    8
  • From page
    161
  • To page
    168
  • Abstract
    The role of mitochondrial DNA (mtDNA) damage in ageing processes and in malignant transformation of a cell is discussed. A mathematical model of the mtDNA population in a cell and in tissue is constructed. The model describes the effects of mtDNA damages accumulated during ageing and some features of malignant transformation and regeneration.
  • Journal title
    Journal of Theoretical Biology
  • Serial Year
    1995
  • Journal title
    Journal of Theoretical Biology
  • Record number

    1532533