Title of article :
Simulation of drug uptake in a two compartmental fractional model for a biological system
Author/Authors :
Petr??، نويسنده , , Ivo and Magin، نويسنده , , Richard L.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2011
Abstract :
This paper presents a very effective numerical method for the solution of the two-compartmental pharmacokinetic model for oral drug administration. This model consists of a set of two fractional order differential equations which connect the two compartments. The first compartment represents the gut while the second compartment corresponds to the drug concentration in the target tissue. For ease of computation, the numerical solution is also created as a Matlab function.
Keywords :
fractional calculus , Compartmental model , Fractional kinetics
Journal title :
Communications in Nonlinear Science and Numerical Simulation
Journal title :
Communications in Nonlinear Science and Numerical Simulation