Title of article
A stochastic model in tumor growth
Author/Authors
Albano، نويسنده , , G. and Giorno، نويسنده , , V.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
8
From page
329
To page
336
Abstract
A stochastic model of solid tumor growth based on deterministic Gompertz law is presented. Tumor cells evolution is described by a one-dimensional diffusion process limited by two absorbing boundaries representing healing threshold and patient death (carrying capacity), respectively. Via a numerical approach the first exit time problem is analysed for the process inside the region restricted by the boundaries. The proposed model is also implemented to simulate the effects of a time-dependent therapy. Finally, some numerical results are obtained for the specific case of a parathyroid tumor.
Keywords
Tumor cells kinetic , diffusion process , Ornstein–Uhlenbeck process , First exit time problem , Gompertz equation
Journal title
Journal of Theoretical Biology
Serial Year
2006
Journal title
Journal of Theoretical Biology
Record number
1537958
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