• Title of article

    Base pair stacking in nucleosome DNA and bendability sequence pattern

  • Author/Authors

    Trifonov، نويسنده , , Edward N.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    3
  • From page
    337
  • To page
    339
  • Abstract
    DNA deformation in the nucleosome involves partial unstacking between bases and base pairs. By adjusting orientations of different base-pair stacks relative to the histone octamer surface, the optimal set of stacks and their positions is derived, resulting in a sequence pattern, theoretically best suitable for nucleosome DNA. The sequence is very much consistent with available experimental data, thus, suggesting a common eukaryotic nucleosome DNA bendability sequence pattern based exclusively on the very basics of DNA.
  • Keywords
    Chromatin code , DNA deformation , nucleosome positioning , Chromatin , DNA minor grooves , Nucleosome DNA sequence
  • Journal title
    Journal of Theoretical Biology
  • Serial Year
    2010
  • Journal title
    Journal of Theoretical Biology
  • Record number

    1540051