• Title of article

    Sampling-through-time in birth–death trees

  • Author/Authors

    Stadler، نويسنده , , Tanja، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    9
  • From page
    396
  • To page
    404
  • Abstract
    I consider the constant rate birth–death process with incomplete sampling. I calculate the density of a given tree with sampled extant and extinct individuals. ensity is essential for analyzing datasets which are sampled through time. Such datasets are common in virus epidemiology as viruses in infected individuals are sampled through time. Further, such datasets appear in phylogenetics when extant and extinct species data is available. how the derived tree density can be used (i) as a tree prior in a Bayesian method to reconstruct the evolutionary past of the sequence data on a calender-timescale, (ii) to infer the birth- and death-rates for a reconstructed evolutionary tree, and (iii) for simulating trees with a given number of sampled extant and extinct individuals which is essential for testing evolutionary hypotheses for the considered datasets.
  • Keywords
    Sampling-through-time , Birth–death process , Tree prior
  • Journal title
    Journal of Theoretical Biology
  • Serial Year
    2010
  • Journal title
    Journal of Theoretical Biology
  • Record number

    1540391