Title of article
A compact result for the time-dependent probability of fixation at a neutral locus
Author/Authors
Waxman، نويسنده , , D.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
5
From page
131
To page
135
Abstract
A result is derived, in the form of a sum, for the time-dependent probability of fixation of an unlinked neutral locus. The result captures many of the key features of the probability of fixation in a highly compact form. For ‘small’ times ( t ≲ 4 N e ) a single term of the sum accurately determines the time-dependent probability of fixation. This is in contrast to the well-known result of Kimura, which requires the contribution of many terms in a different sum, for ‘small’ times. Going beyond small times, an approximation is derived for the time-dependent probability of fixation which applies for all times when the initial relative allele frequency is small.
Keywords
Gene fixation , Neutral theory , Random genetic drift , Wright–Fisher model , Diffusion approximation
Journal title
Journal of Theoretical Biology
Serial Year
2011
Journal title
Journal of Theoretical Biology
Record number
1540574
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