• Title of article

    A compact result for the time-dependent probability of fixation at a neutral locus

  • Author/Authors

    Waxman، نويسنده , , D.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2011
  • Pages
    5
  • From page
    131
  • To page
    135
  • Abstract
    A result is derived, in the form of a sum, for the time-dependent probability of fixation of an unlinked neutral locus. The result captures many of the key features of the probability of fixation in a highly compact form. For ‘small’ times ( t ≲ 4 N e ) a single term of the sum accurately determines the time-dependent probability of fixation. This is in contrast to the well-known result of Kimura, which requires the contribution of many terms in a different sum, for ‘small’ times. Going beyond small times, an approximation is derived for the time-dependent probability of fixation which applies for all times when the initial relative allele frequency is small.
  • Keywords
    Gene fixation , Neutral theory , Random genetic drift , Wright–Fisher model , Diffusion approximation
  • Journal title
    Journal of Theoretical Biology
  • Serial Year
    2011
  • Journal title
    Journal of Theoretical Biology
  • Record number

    1540574