Global properties for virus dynamics model with mitotic transmission and intracellular delay

In this paper we study the basic model of viral infections with mitotic transmission and intracellular delay discrete. The delay corresponds to the time between infection of uninfected cells and the emission of virus on a cellular level. By means of Volterra-type Lyapunov functionals, we provide the global stability for this model. Let η be the number of virus produced per infected cell. If η crit , the critical number, satisfies η ⩽ η crit , then the virus-free steady state is globally asymptotically stable. On the contrary if η > η crit , then the infected steady state is globally asymptotically stable if a sufficient condition is satisfied.