• Title of article

    Estimating the distribution of the G2 phase duration from flow cytometric histograms

  • Author/Authors

    Larsson، نويسنده , , Sara and Ryden، نويسنده , , Tobias and Holst، نويسنده , , Ulla and Oredsson، نويسنده , , Stina and Johansson، نويسنده , , Maria، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2008
  • Pages
    17
  • From page
    1
  • To page
    17
  • Abstract
    A mathematical model, based on branching processes, is proposed to interpret BrdUrd DNA FCM-derived data. Our main interest is in determining the distribution of the G2 phase duration. Two different model classes involving different assumptions on the distribution of the G2 phase duration are considered. Different assumptions of the G2 phase duration result in very similar distributions of the S phase duration and the estimated means and standard deviations of the G2 phase duration are all in the same range.
  • Keywords
    Cell cycle progression , G2 phase duration , flow cytometry , Branching process
  • Journal title
    Mathematical Biosciences
  • Serial Year
    2008
  • Journal title
    Mathematical Biosciences
  • Record number

    1589170