Title of article
Analysis of a kinetic cellular model for tumor-immune system interaction
Author/Authors
Iori، نويسنده , , M. and Nespi، نويسنده , , G. and Spiga، نويسنده , , G.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1999
Pages
13
From page
117
To page
129
Abstract
Starting at a kinetic level from the equations for the evolution of dominance in populations of interacting organisms, and taking proliferative and destructive encounters into account, a simple model describing the competition between tumor cells and immune system is studied in some detail. Under reasonable assumptions, a closed set of macroscopic balance equations for macroscopic observables is derived by a moment procedure, and analyzed in the frame of the theory of dynamical systems. It is shown that a transcritical bifurcation of equilibria generates a region in the phase space in which, according to the model, the immune system defeats the tumor and leads to its depletion. Numerical results are presented and briefly commented on.
Keywords
Nonlinear integro-differential equations , Cellular dynamics , Moment method , dynamical systems , Bifurcation phenomena
Journal title
Mathematical and Computer Modelling
Serial Year
1999
Journal title
Mathematical and Computer Modelling
Record number
1591414
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