• Title of article

    Analysis of a kinetic cellular model for tumor-immune system interaction

  • Author/Authors

    Iori، نويسنده , , M. and Nespi، نويسنده , , G. and Spiga، نويسنده , , G.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1999
  • Pages
    13
  • From page
    117
  • To page
    129
  • Abstract
    Starting at a kinetic level from the equations for the evolution of dominance in populations of interacting organisms, and taking proliferative and destructive encounters into account, a simple model describing the competition between tumor cells and immune system is studied in some detail. Under reasonable assumptions, a closed set of macroscopic balance equations for macroscopic observables is derived by a moment procedure, and analyzed in the frame of the theory of dynamical systems. It is shown that a transcritical bifurcation of equilibria generates a region in the phase space in which, according to the model, the immune system defeats the tumor and leads to its depletion. Numerical results are presented and briefly commented on.
  • Keywords
    Nonlinear integro-differential equations , Cellular dynamics , Moment method , dynamical systems , Bifurcation phenomena
  • Journal title
    Mathematical and Computer Modelling
  • Serial Year
    1999
  • Journal title
    Mathematical and Computer Modelling
  • Record number

    1591414