Title of article
Acute Lymphoblastic Leukemia in Two Patients with B-Thalassemia Major
Author/Authors
Naderi، Majid نويسنده Electrical Engineering Department, , , Miri-Moghaddam، Ebrahim نويسنده Department of Genetics, Genetics of Non-Communicable Disease Research Centre, Zahedan University of Medical Sciences, Zahedan, Iran Miri-Moghaddam, Ebrahim , Alizadeh، Shaban Ali نويسنده Department of Surgery, School of Medicine, Arak University of Medical Sciences, Arak, Iran , , Dorgalaleh، Akbar نويسنده Department of Hematology,Tehran University of Medical Sciences , Tehran, Iran Dorgalaleh, Akbar , Tabibian، Shadi نويسنده Department of Hematology, Tehran University of Medical Sciences, Tehran, Iran Tabibian, Shadi
Issue Information
فصلنامه با شماره پیاپی 0 سال 2014
Pages
2
From page
50
To page
51
Abstract
Occurrence of leukemia in thalassemia major is a rare presentation. Here we report two cases of thalassemic patients, developing acute lymphoblastic leukemia. The genetic analysis revealed that, female and male patients were homozygous for IVSI-6 and IVSI-5, respectively. Two years ago the female patient presented by a high leukocyte count (154,000 µL) and male one also presented by 80,000 WBC/µL count 1 year ago. Microscopic examination of both patients revealed lymphoblasts that morphologically accommodate with ALL-L1 that were confirmed by photocytometry.
Journal title
Zahedan Journal of Research in Medical Sciences
Serial Year
2014
Journal title
Zahedan Journal of Research in Medical Sciences
Record number
1594954
Link To Document