Title of article
Novel synthetic methodologies for fluorination and perfluoroalkylation
Author/Authors
Adams، نويسنده , , Dave J and Clark، نويسنده , , James H and Heath، نويسنده , , Paul A and Hansen، نويسنده , , Liv B and Sanders، نويسنده , , Victoria C and Tavener، نويسنده , , Stewart J، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
5
From page
187
To page
191
Abstract
Nucleophilic routes to selectively fluorinated aromatic compounds starting from cheap and readily available nitroaromatics are reviewed. Me3SiCF3, in conjunction with a fluoride, can be used as either a fluorinating or trifluoromethylating agent, and is capable of both the trifluoromethyldenitration and trifluoromethyldecyanation of an aromatic molecule. Nucleophilic trifluoromethylthiolation can be achieved using thiophosgene and a fluoride.
Keywords
fluorination , Fluorodenitration , Perfluoroalkylation , Trifluoromethyltrimethylsilane
Journal title
Journal of Fluorine Chemistry
Serial Year
2000
Journal title
Journal of Fluorine Chemistry
Record number
1602847
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