Title of article
Fluorinated ketene dithioacetals: 6. Synthesis of α-trifluoromethyl-γ-lactams from bis(ethylsulfanyl)(tetrafluoroethylidene)methane
Author/Authors
Hénin، نويسنده , , Béatrice and Huot، نويسنده , , Jean-François and Portella، نويسنده , , Charles، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
3
From page
281
To page
283
Abstract
A method is proposed for the synthesis of α-trifluoromethyl-γ-lactams (3-trifluoromethyl pyrrolidin-2-ones) by reductive amination of a γ-keto-α-trifluoromethyl thiol ester. The latter is prepared in high yield from the perfluoroketene dithioacetal obtained from perfluoropropanal hydrate.
Keywords
Trifluoromethyl , ?-Lactam , Ketenedithioacetal , Organofluorine
Journal title
Journal of Fluorine Chemistry
Serial Year
2001
Journal title
Journal of Fluorine Chemistry
Record number
1603071
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