Title of article :
Synthesis of novel chiral quaternary phosphonium fluorides: reagents for simple asymmetric nucleophilic fluorination reactions
Author/Authors :
Beaumont، نويسنده , , Andrew J. and Kiely، نويسنده , , Christopher and Denise Rooney، نويسنده , , A.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
The novel chiral quaternary salt (RP)-benzylmenthylmethylphenylphosphonium fluoride was synthesised. The compound was used in the asymmetric nucleophilic fluorination of 2-bromopropiophenone to give 2-fluoropropiophenone in a 35% yield with [α]D20=+1.94°.
Keywords :
asymmetric , nucleophilic , fluorination , Chiral , Phosphonium , fluoride
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
