Title of article :
Solution and solid-phase synthesis of trifluoromethyl peptides and mimetics
Author/Authors :
Bravo، نويسنده , , Pierfrancesco and Bruché، نويسنده , , Luca and Pesenti، نويسنده , , Cristina and Viani، نويسنده , , Fiorenza and Volonterio، نويسنده , , Alessandro and Zanda، نويسنده , , Matteo، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2001
Abstract :
This paper reviews the solution-phase synthesis of trifluoromethyl (Tfm)-analogues of bioactive peptides, such as RGD-peptides and the aspartyl protease inhibitor pepstatin, and the solution/solid-phase synthesis of Tfm-substituted retro- and retro-inverso peptides and hydroxamates.
Keywords :
asymmetric synthesis , solid-phase synthesis , Peptidomimetics , Peptides , Trifluoromethyl group
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
