Title of article :
A novel approach to the synthesis of 5-trifluoromethyl-3-substituted pyrazoles
Author/Authors :
Krishnaiah، نويسنده , , A and Narsaiah، نويسنده , , B، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
The 3-cyano-4-trifluoromethyl-6-phenyl or substituted phenyl 2(1H) pyridones (1) on reaction with hydrazine hydrate, gave exclusively in 5-trifluoromethyl-3-substituted pyrazoles (3) through a novel method. A possible mechanistic pathway for change in the site of nucleophilic attack due to the CF3 group in 2(1H) pyridones is described.
Keywords :
2(1H) pyridones , Bis-nucleophiles , pyrazoles
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry