Title of article
Nucleophilic difluoromethylation and difluoromethylenation using bromodifluoromethyl phenyl sulfone
Author/Authors
Prakash، نويسنده , , G.K. Surya and Wang، نويسنده , , Ying and Hu، نويسنده , , Jinbo and Olah، نويسنده , , George A.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
7
From page
1361
To page
1367
Abstract
Tetrakis(dimethylamino)ethylene (TDAE) was found to be an effective electron-transfer agent that promoted the reactions of bromodifluoromethyl phenyl sulfone with aldehydes to give structurally diverse (benzenesulfonyl)difluoromethylated alcohols in good yield, which can be further transformed into difluoromethyl alcohols and 1,1-difluoro-1-alkenes via reductive desulfonylation and Julia olefination, respectively.
Keywords
Bromodifluoromethyl phenyl sulfone , fluorine , Difluoromethyl alcohol , 1-Difluoro-1-alkene , 1
Journal title
Journal of Fluorine Chemistry
Serial Year
2005
Journal title
Journal of Fluorine Chemistry
Record number
1603747
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