Title of article :
Synthesis of new fluorine-containing dihydrobenzo[c]acridines from trifluoroacetyl dihydronaphthalene and substituted anilines
Author/Authors :
Bonacorso، نويسنده , , Helio G. and Drekener، نويسنده , , Roberta L. and Rodrigues، نويسنده , , Isadora R. and Vezzosi، نويسنده , , Renata P. and Costa، نويسنده , , Michelle B. and Martins، نويسنده , , Marcos A.P. and Zanatta، نويسنده , , Nilo، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A convenient method for the synthesis of a novel series of 7-trifluoromethyl-5,6-dihydrobenzo[c]acridines, in 44–82% yields, by intramolecular cyclization reactions of N-aryl-2-trifluoroacetyl-3,4-dihydronaphthylamines using poly-phosphoric acid (PPA), is described on this paper. Naphthylamine derivatives are obtained by an oxygen-nitrogen exchange reaction from 1-methoxy-2-trifluoroacetyl-3,4-dihydronaphthalene with substituted anilines.
Keywords :
Benzoacridines , Naphthylamine , naphthalene , Acridines , PPA
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry