Title of article :
Hexafluoroacetone as protecting and activating reagent: reactions of hexafluoroacetone with α-keto acids
Author/Authors :
Spengler، نويسنده , , Jan and Osipov، نويسنده , , Sergej N. and Heistracher، نويسنده , , Elisabeth and Haas، نويسنده , , Alois and Burger، نويسنده , , Klaus، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Hexafluoroacetone and α-keto acids react to give 5,5-bis(trifluoromethyl) substituted 2(5H)-furanones and/or 2,2-bis(trifluoromethyl)-1,3-dioxolan-4-ones depending upon the substituent pattern of the side chain of the acid. A fluoroanalogue of the natural product zymonic acid was obtained from ethyl 3,3,3-trifluoropyruvate and 2-oxosuccinic acid in one step.
Keywords :
Hexafluoroacetone , 3-dioxolan-4-ones , 2 , ?-Keto acids , 5 , 5-Bis(trifluoromethyl)-2(5H)-furanones , 5-Trifluoromethyl-2(5H)-furanones , butenolides , Zymonic acid , 2-Bis(trifluoromethyl)-1
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
