Title of article
Microwave-assisted rapid electrophilic fluorination of 1,3-dicarbonyl derivatives with Selectfluor®
Author/Authors
Xiao، نويسنده , , Ji-Chang and Shreeve، نويسنده , , Jean’ne M.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
473
To page
476
Abstract
A microwave-assisted fluorination method for 1,3-dicarbonyl compounds using Selectfluor® has been developed. 2-Monofluorinated products can be obtained in high yield in neutral reaction conditions with addition of 1 eq. of Selectfluor®. Treatment of 1,3-dicarbonyls with 3 eq. of Selectfluor® in the presence of tetrabutylammonium hydroxide (TBAH) as the base results in the formation of 2,2-difluorinated derivatives only.
Keywords
Selectfluor , 1 , 3-Dicarbonyl compounds , microwave , Electrophilic fluorination
Journal title
Journal of Fluorine Chemistry
Serial Year
2005
Journal title
Journal of Fluorine Chemistry
Record number
1608852
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