Title of article
The effect of fluoromethyl groups on the diastereoselectivity in the electrophilic alkylation
Author/Authors
Tamura، نويسنده , , Kenji and Yamazaki، نويسنده , , Takashi and Kitazume، نويسنده , , Tomoya and Kubota، نويسنده , , Toshio، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
13
From page
918
To page
930
Abstract
The effect of fluoromethyl groups on the diastereoselectivity in the electrophilic alkylation is described. In particular, the electrophilic alkylation of enolates with a trifluoromethyl group was proceeded with highly diastereofacial selectivity based on the steric and/or electrostatic effect of substituent with strong electron withdrawing.
Keywords
diastereoselectivity , Electrophilic alkylation
Journal title
Journal of Fluorine Chemistry
Serial Year
2005
Journal title
Journal of Fluorine Chemistry
Record number
1609004
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