Title of article :
The chemical transformation of β-bromodifluoromethyl β-enaminoketones: Synthesis of difluoromethylene thioether compounds
Author/Authors :
Wu، نويسنده , , Yongming and Li، نويسنده , , Ya and Deng، نويسنده , , Juan، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A series of 2-bromodifluoromethylquinoline derivatives were synthesized by cyclization of β-bromodifluoromethyl β-enaminoketones catalyzed by polyphosphoric acid. Difluoromethylene thioether or ether derivatives of quinoline and but-2-en-1-one were obtained by the subustitute reaction of CF2Br with thio- and oxygen nucleophiles.
Keywords :
?-Bromodifluoromethyl ?-enaminoketones , Difluoromethylene thioether , 2-Bromodifluoromethyl-quinoline , cyclization , Gem-difluorinated quinolines , thiophenols , nucleophilic substitution
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
