Title of article
Functional tetrahydroquinoxalines from perfluoroaromatic precursors
Author/Authors
Sandford، نويسنده , , Graham and Tadeusiak، نويسنده , , Andrzej and Yufit، نويسنده , , Dmitrii S. and Howard، نويسنده , , Judith A.K.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
1216
To page
1220
Abstract
A short series of bromo- and nitro-polyfluorobenzene derivatives gave the corresponding tetrahydroquinoxaline systems upon reaction with N,N′-dimethylethylene diamine. This annelation strategy gives useful quantities of functionalised tetrahydroquinoxaline systems which may be interesting scaffolds for the drug discovery arena.
Keywords
Tetrahydroquinoxaline , nucleophilic aromatic substitution , Bicyclic nitrogen heterocycle , Fluoroaromatic , Scaffold
Journal title
Journal of Fluorine Chemistry
Serial Year
2007
Journal title
Journal of Fluorine Chemistry
Record number
1609892
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