Title of article :
Fluoride-induced coupling of perfluoroketene dithioacetals with silyl alkynes: A way towards new polyfunctionalized trifluoromethyl building blocks
Author/Authors :
Nocentini، نويسنده , , Tiziano and Brulé، نويسنده , , Cédric and Bouillon، نويسنده , , Jean-Philippe and Gouault-Bironneau، نويسنده , , Sonia and Portella، نويسنده , , Charles، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
Under fluoride activation, the vinyl fluorine of perfluoroketene dithioacetal may be substituted by silylated nucleophiles. Using silyl alkynes, a formal transition metal free sila-Sonogashira cross-coupling reaction occurred. The resulting enynes were hydrolyzed giving new polyfunctional trifluoromethyl building blocks.
Keywords :
Ketene dithioacetal , cross-coupling , Fluorine substitution , Sila-Sonogashira , Trifluoromethyl building blocks , Silyl alkynes
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
