Title of article
A facile stereoselective synthesis of 2-perfluoroalkyl-3a,4,5,6-tetrahydroimidazo[1,5-b]isoxazoles
Author/Authors
Lu، نويسنده , , Lei and Cao، نويسنده , , Weiguo and Chen، نويسنده , , Jie and Zhang، نويسنده , , Hui and Zhang، نويسنده , , Jiaping and Chen، نويسنده , , Huiyun and Wei، نويسنده , , Jiamei and Deng، نويسنده , , Hongmei and Shao، نويسنده , , Min، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
6
From page
295
To page
300
Abstract
Methyl 2-perfluoroalkynoates 2 reacted readily with cyclic nitrones 1 via 1,3-dipolar cycloaddition at room temperature to give 2-perfluoroalkyl-3a,4,5,6-tetrahydroimidazo[1,5-b]isoxazoles 3 in good to excellent yields with high diastereoselectivity and regioselectivity.
Keywords
Methyl 2-perfluoroalkynoates , Imidazoisoxazoles , 1 , regioselectivity , diastereoselectivity , 3-dipolar cycloaddition
Journal title
Journal of Fluorine Chemistry
Serial Year
2009
Journal title
Journal of Fluorine Chemistry
Record number
1610426
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