Title of article
Asymmetric aldol reactions using chiral CF3-Oxazolidines (Fox) as chiral auxiliary
Author/Authors
Tessier، نويسنده , , Arnaud and Pytkowicz، نويسنده , , Julien and Brigaud، نويسنده , , Thierry، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
5
From page
1140
To page
1144
Abstract
The aldol reactions of amide enolates derived from a trifluoromethylated oxazolidine (Fox) chiral auxiliary occur in good yields with a moderate anti diastereoselectivity (Li and Na enolates) to a high syn diastereoselectivity (boron enolate). After removal, the Fox chiral auxiliary is very conveniently and efficiently recovered in basic conditions.
Keywords
aldol reaction , Oxazolidines , Organofluorine chemistry , stereoselective synthesis
Journal title
Journal of Fluorine Chemistry
Serial Year
2009
Journal title
Journal of Fluorine Chemistry
Record number
1610714
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