Title of article
Oxidative detagging of fluorous organosilanes
Author/Authors
Boldon، نويسنده , , Sophie and Moore، نويسنده , , Jane E. and Gouverneur، نويسنده , , Véronique، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2009
Pages
6
From page
1151
To page
1156
Abstract
We have validated a novel detagging strategy featuring the unmasking of a fluorous-tagged silane to a hydroxy moiety. The fluorous silylated bicyclononane, prepared from the titanium-mediated annulation of 1-acetylcyclohexene and a fluorous-tagged allylsilane, was successfully detagged under Fleming-type oxidation conditions. The stereochemistry of the resulting hydroxylated product indicates retention of configuration upon detagging in line with the non-fluorous variant of this transformation.
Keywords
annulation , Oxidative detagging , Silicon , fluorous
Journal title
Journal of Fluorine Chemistry
Serial Year
2009
Journal title
Journal of Fluorine Chemistry
Record number
1610717
Link To Document