Title of article :
A facile and efficient synthesis of β-amino alcohols using 2,2,2-trifluoroethanol as a metal-free and reusable medium
Author/Authors :
Khaksar، نويسنده , , Samad and Heydari، نويسنده , , Akbar and Tajbakhsh، نويسنده , , Mahmood and Bijanzadeh، نويسنده , , Hamid Reza، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2010
Abstract :
Trifluoroethanol was used as a reusable catalyst and medium for the ring opening of epoxides using aliphatic and aromatic amines as nucleophile under mild conditions to give the corresponding β-amino alcohols in high yields and regioselectivity.
Keywords :
?-Amino alcohols , regioselectivity , Hydrogen bonding , TFE
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry