Title of article
Reaction of enamines with trifluoromethyl containing carbonyl reagents
Author/Authors
Sibgatulin، نويسنده , , Dmitriy A. and Shubina، نويسنده , , Tatyana E. and Kostyuk، نويسنده , , Aleksandr N. and Volochnyuk، نويسنده , , Dmitriy M. and Schmutzler، نويسنده , , Reinhard and Jones، نويسنده , , Peter G. and Pinchuk، نويسنده , , Aleksandr M. Kuznetsov، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
10
From page
190
To page
199
Abstract
The reaction of linear push–pull enamines bearing a methyl group at the α-position with a set of trifluoromethylated carbonyl compounds was investigated. It has been found that the reaction proceeds at the methyl group of the enamines. The first computational study of the reaction between push–pull enamines and strong electrophilic reagents was reported. Out of three pathways considered DFT and MP2 calculations support ene-mechanism previously suggested based on experimental results only.
Keywords
Trifluoromethyl ketones , enamines , Electrophilic functionalization , DFT , Ene-reaction
Journal title
Journal of Fluorine Chemistry
Serial Year
2010
Journal title
Journal of Fluorine Chemistry
Record number
1610790
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