Title of article :
One-pot α-nucleophilic fluorination of acetophenones in a deep eutectic solvent
Author/Authors :
Chen، نويسنده , , Zizhan and Zhu، نويسنده , , Wei and Zheng، نويسنده , , Zubiao and Zou، نويسنده , , Xinzhuo and Qiu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2010
Abstract :
Two methods of nucleophilic fluorination to prepare α-fluoroacetophenones from α-bromoacetophenones by using KF with PEG-400 or TBAF with ZnF2 are described. On the fundamental of nucleophilic fluorination, a novel method of one-pot fluorination to prepare α-fluoroacetophenones directly from acetophenones in DES was developed.
Keywords :
One-pot , Nucleophilic fluorination , ?-Fluoroacetophenones , Deep eutectic solvents
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
