Title of article
Synthesis of fluorinated 2,3-dihydropyran-4-ones by cyclocondensation of 1,3-dicarbonyl dianions with aldehydes
Author/Authors
Khera، نويسنده , , Rasheed Ahmad and Hussain، نويسنده , , Munawar and Ahmad، نويسنده , , Rasheed and Saeed، نويسنده , , Aamer and Villinger، نويسنده , , Alexander and Fischer، نويسنده , , Christine and Langer، نويسنده , , Peter، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
6
From page
892
To page
897
Abstract
The reaction of the dianion of 1,1,1-trifluoro-pentane-2,4-dione with aldehydes and subsequent addition of hydrochloric acid afforded 2,3-dihydro-6-trifluoromethyl-pyran-4-ones. The reaction of the dianion of acetylacetone with fluorinated benzaldehydes gave the corresponding fluorinated 2-aryl-2,3-dihydro-6-methyl-pyran-4-ones. All reactions proceeded in very good yield and with very good regioselectivity.
Keywords
regioselectivity , Pyranones , cyclizations , dianions , O-Heterocycles
Journal title
Journal of Fluorine Chemistry
Serial Year
2010
Journal title
Journal of Fluorine Chemistry
Record number
1610997
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