Title of article :
Synthesis of monofluoroalkenes via Julia–Kocienski reaction
Author/Authors :
Prakash، نويسنده , , G.K. Surya and Shakhmin، نويسنده , , Anton and Zibinsky، نويسنده , , Mikhail and Ledneczki، نويسنده , , Istvan and Chacko، نويسنده , , Sujith and Olah، نويسنده , , George A.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2010
Abstract :
Monofluoromethyl 3,5-bis(trifluoromethyl)phenyl sulfone 1 was synthesized and employed in Julia–Kocienski fluoroolefination reaction with various ketones and aldehydes. Optimal reaction conditions were found to be the treatment of substrates with KOH or CsF in DMSO at room temperature. Mixtures of (E) and (Z) isomers of monofluoroalkenes 4 were obtained in moderate to excellent yields.
Keywords :
Monofluoroalkenes , Monofluoromethyl arylsulfone , Julia–Kocienski reaction , Monofluoroolefination
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
