Title of article
Synthesis of monofluoroalkenes via Julia–Kocienski reaction
Author/Authors
Prakash، نويسنده , , G.K. Surya and Shakhmin، نويسنده , , Anton and Zibinsky، نويسنده , , Mikhail and Ledneczki، نويسنده , , Istvan and Chacko، نويسنده , , Sujith and Olah، نويسنده , , George A.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
6
From page
1192
To page
1197
Abstract
Monofluoromethyl 3,5-bis(trifluoromethyl)phenyl sulfone 1 was synthesized and employed in Julia–Kocienski fluoroolefination reaction with various ketones and aldehydes. Optimal reaction conditions were found to be the treatment of substrates with KOH or CsF in DMSO at room temperature. Mixtures of (E) and (Z) isomers of monofluoroalkenes 4 were obtained in moderate to excellent yields.
Keywords
Monofluoroalkenes , Monofluoromethyl arylsulfone , Julia–Kocienski reaction , Monofluoroolefination
Journal title
Journal of Fluorine Chemistry
Serial Year
2010
Journal title
Journal of Fluorine Chemistry
Record number
1611081
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