Title of article
Chiral bifunctional thiourea-catalyzed enantioselective aldol reaction of trifluoroacetaldehyde hemiacetal with aromatic ketones
Author/Authors
Nie، نويسنده , , Jing and Li، نويسنده , , Xiao-Juan and Zheng، نويسنده , , Donghua and Zhang، نويسنده , , Fa-Guang and Cui، نويسنده , , Shumin and Ma، نويسنده , , Jun-An، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
6
From page
468
To page
473
Abstract
In the presence of saccharide-derived bifunctional amine-thiourea catalysts, the direct aldol condensation of trifluoroacetaldehyde methyl hemiacetal with aromatic ketones proceeds to produce (R)-β-hydroxy β-trifluoroalkyl ketones in low to moderate yields with good enantioselectivities.
Keywords
Trifluoroacetaldehyde , aldol , Saccharide , Thiourea , bifunctional organocatalyst
Journal title
Journal of Fluorine Chemistry
Serial Year
2011
Journal title
Journal of Fluorine Chemistry
Record number
1611289
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