Title of article
1,4-Additions of electron-rich heterocycles onto β-perfluoroalkyl enones
Author/Authors
Leuger، نويسنده , , Julia and Blond، نويسنده , , Gaelle and Billard، نويسنده , , Thierry and Haufe، نويسنده , , Günter and Langlois، نويسنده , , Bernard R.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2011
Pages
5
From page
799
To page
803
Abstract
β-(Trifluoromethyl) enones, easily obtained in few steps from commercially available methyl hemiketal of trifluoroacetaldehyde, react with electron-rich O- and N-containing heterocycles (furans and benzofurans, pyrroles and indoles, hydroxycoumarins), through a 1,4 addition, to give heterocycles bearing a functionalized side-chain. β-(chlorodifluoromethyl)enones and β-(pentafluoroethyl)enones behave in the same way.
Keywords
?-(Trifluoromethyl)enones , ?-(Perfluoroalkyl)enones , Heterocycles , Benzofurans , pyrroles , indoles , hydroxycoumarins , Side-chain perfluoroalkylated heterocycles , 4-addition , Perfluoroalkyl Warfarin analogs , 1 , Furans
Journal title
Journal of Fluorine Chemistry
Serial Year
2011
Journal title
Journal of Fluorine Chemistry
Record number
1611378
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