Title of article
Synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H-quinazolin-4-ones
Author/Authors
Nosova، نويسنده , , Emiliya V. and Lipunova، نويسنده , , Galina N. and Slepukhin، نويسنده , , Pavel A. and Charushin، نويسنده , , Valery N.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
3
From page
63
To page
65
Abstract
A versatile pathway for the synthesis of 7-cycloalkylimino substituted 3-amino-6-fluoro-2-methyl-3H-quinazolin-4-ones from 4,5-difluoroanthranylic acid has been advanced. Nucleophilic amination–defluorination reaction of the 6,7-difluoro derivative of 3-amino-2-methyl-3H-quinazolin-4-one has been established to occur at position 7, as shown by X-ray crystallographic analysis.
Keywords
Fluorine-containing quinazolinones , 3-Aminoquinazolin-4-ones , Nucleophilic displacement reactions , X-ray crystallography
Journal title
Journal of Fluorine Chemistry
Serial Year
2013
Journal title
Journal of Fluorine Chemistry
Record number
1611937
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