Title of article
Synthesis and characterization of fluorinated derivatives of cresolsulfonphthalein
Author/Authors
Kachur، نويسنده , , Alexander V. and Sardelis، نويسنده , , Diana and Bentzley، نويسنده , , Catherine and Popov، نويسنده , , Anatoliy V. and Delikatny، نويسنده , , E. James and Karp، نويسنده , , Joel، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
6
From page
112
To page
117
Abstract
The reaction between dilute fluorine gas and cresolsulfonphthalein in acetic acid was investigated. The mono-, di-, and trifluorinated cresolsulfonphthalein derivatives were isolated and characterized. These compounds possessed the properties of pH indicators with biologically relevant pKa values (6.4–7.5) and the absorption maxima of the basic forms at 582–592 nm. This method can be used for synthesis of positron-emitting 18F-labeled pH indicators with potential application for non-invasive in vivo pH measurement in biological objects.
Keywords
fluorine , Cresol Purple , Electrophilic fluorination , pH measurement
Journal title
Journal of Fluorine Chemistry
Serial Year
2013
Journal title
Journal of Fluorine Chemistry
Record number
1611945
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