Title of article :
The enantioselective trifluoromethylation of aromatic aldehydes by quaternary ammonium bromide and (IPr)CuF at low catalyst loading
Author/Authors :
Wu، نويسنده , , Shaoxiang and Guo، نويسنده , , Jiyi and Sohail، نويسنده , , Muhammad and Cao، نويسنده , , Chengyao and Chen، نويسنده , , Fu-Xue، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2013
Abstract :
A general catalytic enantioselective trifluoromethylation of aromatic aldehydes using (IPr)CuF and quinidine-derived quaternary ammonium salt as catalysts has been developed. A wide range of aromatic aldehydes are converted to the corresponding products in up to 92% yield and 81% ee at 2 mol% of catalyst loading.
Keywords :
aldehyde , Carbene copper species , trifluoromethylation , Quaternary ammonium salt , Asymmetric catalysis
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
