Author/Authors :
Bian، نويسنده , , Linglin and Lu، نويسنده , , Xuesheng and Xu، نويسنده , , Jiechao and Chen، نويسنده , , Jie and Deng، نويسنده , , Hongmei and Shao، نويسنده , , Min and Jin، نويسنده , , Yong and Zhang، نويسنده , , Hui and Cao، نويسنده , , Weiguo، نويسنده ,
Abstract :
The synthesis of 2-perfluoroalkylated benzoxazolines and benzothiazolines was easily achieved under mild conditions in high yields and purity. The protocol uses readily available methyl 2-perfluoroalkynoates as fluorine-containing building block, and furnished the expected product in good to excellent yields in MeOH under reflux for 10 h. This novel synthetic protocol is efficient and general. A plausible mechanism for this process is proposed.
Keywords :
Perfluoroalkylated , Synthesis , Methyl 2-perfluoroalkynoate , Benzoxazoline , Benzothiazoline
