Title of article
Straightforward synthesis of 2-propylquinolines under multicomponent conditions in fluorinated alcohols
Author/Authors
Venkateswarlu، نويسنده , , Ch. and Balaji، نويسنده , , P.V. and De، نويسنده , , Kavita and Crousse، نويسنده , , Benoit and Figadère، نويسنده , , Bruno and Legros، نويسنده , , Julien، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
5
From page
94
To page
98
Abstract
The synthesis of 2-propylquinolines, a family of antileishmanial agents, is reported. Among the pathways explored, the 3-component Povarov reaction between butyraldehyde, aromatic amines and ethyl vinyl ether in trifluoroethanol (TFE), followed by an oxidation, offers a convenient entry to 2-propylquinolines with various substituents on positions 5–8.
Keywords
Domino reaction , Michael addition , HFIP , Aniline , Heterocycles
Journal title
Journal of Fluorine Chemistry
Serial Year
2013
Journal title
Journal of Fluorine Chemistry
Record number
1612048
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