Title of article
Synthesis of fluorinated pyrimidinones
Author/Authors
Kosobokov، نويسنده , , Mikhail D. and Struchkova، نويسنده , , Marina I. and Arkhipov، نويسنده , , Dmitry E. and Korlyukov، نويسنده , , Alexander A. and Dilman، نويسنده , , Alexander D.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2013
Pages
7
From page
73
To page
79
Abstract
A method for the construction of fluorinated pyrimidinones based on the reaction of cyanodifluoromethyl-substituted amines with isocyanates is described. The use of ortho-iodophenylisocyanate in this reaction followed by copper catalyzed intramolecular amination affords fluorinated fused heterocycles – 4-fluoropyrimido[1,6-a]benzimidazol-1(2H)-ones.
Keywords
Coupling reaction , Pyrimidinones , cyclization , Isocyanates , Heterocycles
Journal title
Journal of Fluorine Chemistry
Serial Year
2013
Journal title
Journal of Fluorine Chemistry
Record number
1612098
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